Enhanced apoptosis and electrostatic acetylcholi-nesterase activity of abnormally hydrophobic envi-ronment in alzheimer’s plaques

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چکیده

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Enhanced apoptosis and electrostatic acetylcholi-nesterase activity of abnormally hydrophobic envi-ronment in alzheimer’s plaques

Alzheimer’s disease (AD) is considered a slow neuronal dysfunction process through hypoxia, ischemia and leads to apoptosis mediated senile plaques and neurofibrillary tangles (NFTs). Due to non-invasive approach of plaque characterization, computational techniques based on Brownian dynamics simulation are unique to speculate the electrostatic and kinetic properties of Acetylcholinesterase (ACh...

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ژورنال

عنوان ژورنال: Journal of Biomedical Science and Engineering

سال: 2008

ISSN: 1937-6871,1937-688X

DOI: 10.4236/jbise.2008.13030